Red wine contains resveratrol, which is a plant polyphenol compound with antioxidant, anti-aging and anti-inflammatory effects. It is commonly found in grape skins, peanuts, and cocoa. Resveratrol in plants is generally divided into two forms: trans (trans-) and cis (cis-), among which trans-veratrol is more stable and has a more significant effect on animals, so it has become the current supplement the main ingredient.
In addition to resveratrol’s antioxidant and anti-inflammatory properties, recent large studies have found that it also plays a key role in extending healthy lifespan. Combining 19 clinical studies on different species, scientists found that resveratrol can activate sirtuins, promote the ability of autophagy, and remove wastes in cells, so as to delay the degradation of bodily functions and prolong life.
One of the biggest problems of aging is the decline of various functions, and different studies have found that resveratrol can reduce our risk of cardiovascular disease, neurological decline and other physiological diseases. Dementia (also known as Alzheimer’s disease) is a growing global concern. Even if the disease is still unknown, the academic community believes that the problem of brain degeneration is related to neuroinflammation and the formation of Beta Amyloid (aβ) plaques in the brain. In order to study the efficacy of resveratrol against aging-related diseases, in 2017, Georgetown University School of Medicine in the United States divided 119 patients with Alzheimer’s disease into two groups, one group took resveratrol, while the other group received No. After 52 weeks, using magnetic resonance imaging, the researchers found that the resveratrol-treated group was stable on various neuro-biomarker tests, with improvements in aβ accumulation and brain inflammation, while the other group had persistent symptoms. The signs of deterioration, it can be seen that resveratrol can help protect brain nerve cells and help delay aging-related degenerative diseases.
Scientific research has found that resveratrol can activate longevity genes sirtuins, helping to maintain cell health and prolong their lifespan, but resveratrol alone cannot make sirtuins play the greatest role. Professor David Sinclair from Harvard Medical School proposed that if sirtuins are regarded as a car, resveratrol is the accelerator pedal, and NMN is the fuel of this car to help sirtuins maintain operation, and both are indispensable.